RESEARCH JOURNAL OF PHARMACOLOGY//(VOL. 13, ISSUE 3)
Volumen: 13, Numero: 3, Páginas: 35-41 pp.
Renal cell carcinoma is currently a tumor with an increasing incidence, associated with a higher mortality rate with an equal proportion for both sexes. After 59 years of age, there is an increased risk of kidney cancer as the incidence increases with age. In most cases renal cell carcinoma is discovered incidentally by independent imaging findings in renal pathology and in symptomatic cases the clinical triad consisting of macroscopic hematuria, lumbar fossa pain and presence of palpable mass. Renal clear cell carcinoma was the most frequent histological type with a grade 2 Fuhrman present in the majority of cases. It has been shown that renal tumors can infiltrate the renal capsule, perirenal fat, Gerotaös fascia, renal sinus, renal vein, vena cava and the lymphovascular system. The presence of tumor necrosis is associated with a poor prognosis in patients with renal masses >7cm. The mean tumor size was 7.17 (2-20) cm. The lymph node metastasis is very frequent, being the liver, lungs and bones the anatomical areas more prone to metastasize. The majority of patients diagnosed are in stage 1 and 3. The degree of surgical complexity and the surgical procedure indicate that there is no correlation (p = 0.00) between the imaging report and the surgical evaluation.